Actifed Cold and Allergy (as a combination product containing Chlorpheniramine Maleate and Phenylephrine Hydrochloride), Actifed Cold and Sinus (as a combination product containing Chlorpheniramine Maleate, Pseudoephedrine Hydrochloride, and Acetaminophen), Ah-Chew (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Alka-Seltzer Plus Cold Medicine Liqui-Gels (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Aller-Chlor, Aller-Chlor Syrup, Allerest Maximum Strength (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Atrohist Pediatric (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Brexin L.A. (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Chlo-Amine, Chlordrine S.R. (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Chlor-Phed Timecelles (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Chlor-Trimeton 12 Hour Allergy, Chlor-Trimeton 12 Hour Allergy Decongestant (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Sulfate), Chlor-Trimeton 4 Hour Allergy, Chlor-Trimeton 4 Hour Allergy Decongestant (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Sulfate), Chlor-Trimeton 8 Hour Allergy, Chlor-Trimeton Allergy Syrup, Comhist (as a combination product containing Chlorpheniramine Maleate, Phenylephrine Hydrochloride, and Phenyltoloxamine Citrate), Comtrex Allergy-Sinus Maximum Strength Tablets (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Coricidin HBP Cold & Flu (as a combination product containing Chlorpheniramine Maleate and Acetaminophen), D.A. Chewable (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), D.A. II (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Dallergy (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Dallergy Caplets (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Dallergy Syrup (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Deconamine (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Deconamine SR (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Deconamine Syrup (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Dristan Cold (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Phenylephrine Hydrochloride), Dura-Vent DA (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), EX-Histine Syrup (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Extendryl (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Extendryl Jr. (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Extendryl Sr. (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Extendryl Syrup (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Flu-Relief Caplets (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Histalet Syrup (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Kolephrin Caplets (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Kronofed-A Kronocaps (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Kronofed-A-Jr. Kronocaps (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Mescolor (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Pseudoephedrine Hydrochloride), ND Clear (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), ND-Gesic (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, Phenylephrine Hydrochloride, and Pyrilamine Maleate), Novahistine Elixir (as a combination product containing Chlorpheniramine Maleate and Phenylephrine Hydrochloride), Omnihist LA (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride), Polaramine, Polaramine Expectorant (as a combination product containing Dexchlorpheniramine Maleate, Guaifenesin, and Pseudoephedrine Sulfate), Polaramine Repetabs, Polaramine Syrup, Protid as a (combination product containing Chlorpheniramine Maleate, Acetaminophen, and Phenylephrine Hydrochloride), Rescon (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Rescon JR (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Rescon-ED (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Rhinatate (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), R-Tannate (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), R-Tannate Pediatric (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Ryna (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Rynatan (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Rynatan Pediatric (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Rynatan-S Pediatric (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Sinarest (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Sinarest Extra Strength Caplets (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Sine-Off Sinus Medicine Caplets (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Singlet Caplets (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Sinutab Sinus Allergy Maximum Strength Caplets (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Sinutab Sinus Allergy Maximum Strength Tablets (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Sudafed Cold & Allergy (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Tanafed (as a combination product containing Chlorpheniramine Tannate and Pseudoephedrine Tannate), Tanoral Pediatric (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Tanoral-S Pediatric (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Teldrin Allergy, TheraFlu Flu and Cold Medicine (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), TheraFlu Flu and Cold Medicine for Sore Throat Maximum Strength (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Triaminic Cold & Allergy Softchews (as a combination product containing Chlorpheniramine Maleate and Pseudoephedrine Hydrochloride), Triotann (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Triotann Pediatric (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Triotann-S Pediatric (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Triple Tannate Pediatric Suspension (as a combination product containing Chlorpheniramine Tannate, Phenylephrine Tannate, and Pyrilamine Tannate), Tussi-12 (as a combination product containing Chlorpheniramine Tannate, Carbetapentane Tannate, and Phenylephrine Tannate), Tylenol Allergy Sinus Maximum Strength Caplets (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Tylenol Allergy Sinus Maximum Strength Gelcaps (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Tylenol Allergy Sinus Maximum Strength Geltabs (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Tylenol Cold Multi-Symptom Children's (as a combination product containing Chlorpheniramine Maleate, Acetaminophen, and Pseudoephedrine Hydrochloride), Vanex Forte-R (as a combination product containing Chlorpheniramine Maleate, Methscopolamine Nitrate, and Phenylephrine Hydrochloride)

Chlorpheniramine relieves red, itchy, watery eyes; sneezing; itchy nose or throat; and runny nose caused by allergies, hay fever, and the common cold in adults and children over age 2. Chlorpheniramine should not be given to children younger than 2 years old because it may cause serious or life-threatening side effects in young children. Chlorpheniramine should not be given to children older than 2 years old but younger than 6 years old unless prescribed by a doctor. Chlorpheniramine tablets, capsules, chewable tablets and liquid should be used carefully in children who are 6-11 years old; the extended-release tablets and extended-release capsules should not be given to children in this age group unless prescribed by a doctor. Chlorpheniramine will only relieve the symptoms of cold or allergies but will not treat the cause of the symptoms or speed recovery. Chlorpheniramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms.

Chlorpheniramine comes as a tablet, a capsule, an extended-release (long-acting) tablet and capsule, a chewable tablet, and a liquid to take by mouth. The regular capsules and tablets, chewable tablets, and liquid are usually taken every 4 to 6 hours as needed. The extended-release (long-acting) tablets and capsules are usually taken twice a day in the morning and evening as needed. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take chlorpheniramine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Chlorpheniramine comes alone and in combination with fever and pain reducers, expectorants, cough suppressants, and decongestants. Ask your doctor or pharmacist for advice on which product is best for your symptoms. Check nonprescription cough and cold product labels carefully before using two or more products at the same time. These products may contain the same active ingredient(s) and taking them together could cause you to receive an overdose.This is especially important if you will be giving cough and cold medications to a child.

If you are using the extended-release tablets or capsules, swallow them whole. Do not break, crush, chew, or open them.

If you are using the liquid, do not use a household spoon to measure your dose. Use the measuring spoon or cup that came with the medication or use a spoon made especially for measuring medication.

Chlorpheniramine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• drowsiness
• dry mouth, nose, and throat
• nausea
• vomiting
• loss of appetite
• constipation
• headache
• increased chest congestion

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

• vision problems
• difficulty urinating

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].

• tell your doctor and pharmacist if you are allergic to chlorpheniramine, any other medications, or any of the ingredients in the chlorpheniramine product you plan to use. Check the package label for a list of the ingredients
• tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: other medications for colds, hay fever, or allergies; medications for anxiety, depression or seizures; muscle relaxants; narcotic medications for pain; sedatives; sleeping pills; and tranquilizers.
• tell your doctor if you have or have ever had asthma, emphysema, chronic bronchitis, or other types of lung disease; glaucoma (a condition in which increased pressure in the eye can lead to gradual loss of vision); ulcers; diabetes; difficulty urinating (due to an enlarged prostate gland); heart disease; high blood pressure; seizures; or an overactive thyroid gland.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking chlorpheniramine, call your doctor.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking chlorpheniramine.
• you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
• remember that alcohol can add to the drowsiness caused by this medication.

Chlorpheniramine is usually taken as needed. If your doctor has told you to take chlorpheniramine regularly, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Ask your pharmacist any questions you have about chlorpheniramine.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.